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Pathology 192, 16481657

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The peptide incorporates two key modifications from native GIP: an aminoisobutyric acid (Aib) substitution at position 2 for DPP-4 resistance and a C-20 eicosanedioic fatty diacid moiety linked at Lys20 via a Glu-2xOEG spacer for albumin binding and half-life extension

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Under normal physiological conditions, oxygen-free radicals in the organism are in a dynamic state of equilibrium: oxygen-free radicals are constantly produced and constantly eliminated

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These modes of healing have been observed in rodents with transected Achilles tendons

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